What condition occurs when flexible tissue at the ends of bones wears down?

The condition where flexible tissue at the ends of bones wears down is known as osteoarthritis. This degenerative joint disease primarily affects the cartilage, which is the smooth, flexible tissue that covers the ends of bones in a joint. Over time, with factors such as age, repetitive use, or injury, the cartilage can gradually break down, leading to pain, stiffness, and decreased mobility in the affected joints.

In osteoarthritis, the protective cartilage is lost, resulting in bones rubbing against each other, which can cause inflammation and further joint damage. This condition often affects weight-bearing joints such as the knees and hips, but can also impact the hands and spine. The wear and tear on the cartilage is a key characteristic that distinguishes osteoarthritis from other forms of arthritis, such as rheumatoid arthritis, which is an autoimmune disorder leading to joint inflammation. Understanding the specific mechanisms of osteoarthritis helps in grasping its clinical manifestations and treatment options.