Which syndrome is Epstein-Barr virus also associated with?

Epstein-Barr virus (EBV) is closely associated with Chronic Fatigue Syndrome (CFS). CFS is characterized by extreme fatigue that cannot be explained by any underlying medical condition and can be triggered by an infection, including viral infections like EBV. Research has indicated that individuals who have contracted mononucleosis, which is often caused by EBV, may experience prolonged periods of fatigue and other symptoms consistent with CFS.

This connection is attributed to the immune system's response to the virus, which can lead to lasting effects, symptoms of fatigue, and cognitive dysfunction that align with CFS. While EBV has been studied in relation to other syndromes and conditions, its strongest association recognized in the literature is with Chronic Fatigue Syndrome, making this the best choice in the question provided.